Remember ME - You Me and Dementia

Showing posts with label Thoughts Idea. Show all posts
Showing posts with label Thoughts Idea. Show all posts

April 23, 2012

USA: Seniors shopping for cell phones should be choosy

ORLANDO, Florida / Orlando Sentinel / April 22, 2012

Daniel Vasquez, Sun Sentinel

For many Florida senior citizens, cell phones are not only a matter convenience, they can be a conduit to a safer way of life. But shopping
for the right mobile phone for yourself — or a loved one who is older and not comfortable with today's mobile phone technologies — may be a tough task, given how difficult it is to choose a device that is easy to use and a carrier plan that is not hard on the wallet, particularly for those on a fixed budget.

I know. I just went through the process for my 86-year-old father, who never owned a cell phone.
And that confusion and frustration is shared even by seniors familiar with mobile devices.
Illustrative photograph courtesy: http://cell-phonesforseniors.com/
"I need to find a cell carrier that is affordable and reliable, mostly for phone calls and few text messages," said Silas Pinto, a 60-year-old international business CEO and pastor of Silas Pinto International Ministries in Orlando.
So, what to consider:
Ask questions: AT&T South Florida spokesperson Kelly Layne Starling recommends seniors with phones "have their plan analyzed for savings and to get help [finding] the device that best suits them." 
Devices: My father chose the Samsung Jitterbug, which costs $65 for the device, works on Verizon's network and features large buttons and an easy-to-read display screen. No-contract plans start at $15 a month for 50 minutes. You can also purchase the 5Star Urgent Response service for $15 a month which connects callers to 24-hour medical response teams which use GPS to locate a user in trouble.
Check with your favorite carrier for similar devices and plans. 
This is an abridged version of the report
Copyright © 2012, Orlando Sentinel
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Credit: Reports and photographs are property of owners of intellectual rights.
Seniors World Chronicle, a not-for-profit, serves to chronicle and widen their reach.

September 4, 2011

JAPAN: Priest-philosopher makes death his life's work

TOKYO, Japan / The Japan Times / Life in Japan / Features / September 4, 2011

CLOSE-UP: Alfons Deeken
By Eriko Arita - Staff writer

On Friday, July 22, as the stifling heat and humidity of summer relented for just a fleeting few days, hundreds of people filled a hall at Enkakuji Temple in Kamakura, Kanagawa Prefecture, to listen to a lecture by philosophy scholar Alfons Deeken.

German-born Deeken, a professor emeritus at Sophia University in Tokyo, and long a leading promoter of death education in Japan, told the audience in lively, fluent Japanese that the more you think about your own death, the more you realize how precious your life is — and so the more you will live your life to the full.

"I have been a member of various health ministry committees," the 79-year-old professor said rather solemnly. "And according to the ministry's statistics, the mortality rate of Japanese people is 100 percent." It was his way of stressing that everyone has to face death.

Deeken, who is honorary chairman of Sei to Shi wo Kangaeru Kai (the Japanese Association of Death Education and Grief Counseling), which he founded 1983, then went on to emphasize that learning about death and dying is not a depressing pursuit, but one that leads to a fuller appreciation of life.

Deeken in the Alps, during his time as a student in Munich
During his childhood in wartime Germany, Deeken often encountered death in his family and among his friends, including those who were victims of Allied bombing. However, such experiences — as he explains in one of his books, titled "Yoku Iki Yoku Warai Yoki Shi to Deau" ("Good Living, Good Humor, Good Death") — led him to choose thanatology (the study of death) as his life's work.

Born in 1932 as the third child of a pious Catholic father who was a real estate agent and farmer in Emstek in the northern German state of Lower Saxony, young Deeken helped his anti-Nazi father in various ways, including typing for secret distribution many copies of a speech by a bishop criticizing the regime.

Photo courtesy: University of Human Arts & Sciences

After war's end in 1945, the then teenage Deeken threw himself into the world of books, and it was after he read a biography of St. Francis Xavier that he decided to become a Catholic priest. So, after graduating from high school, he entered the Society of Jesus (the Roman Catholic, all-male, evangelizing Jesuits) in Germany before studying German literature in Austria and then gaining a master's degree in philosophy from a university in Munich.

In 1959, Deeken came to Japan to study Japanese and theology, and he was ordained as a priest in 1965. Then, from 1967 to 1973, he studied for his Ph.D. in philosophy at Fordham University in New York City, an institution "in the Jesuit tradition."

Following the award of his doctorate, in 1973 Deeken started teaching philosophy at Sophia University, including a course titled Shi no Tetsugaku (Philosophy of Death) in 1977. Besides all this and the association he founded in 1983, Deeken has actively promoted death education among the general public and has had about 30 books published in Japanese about death, dying, bereavement and grief — some of which were translated into Korean and Chinese.

Dr. Alfons Deeken gave a keynote speech on spiritual healing and humor at a study session on "Thinking about Life and Death: How We Should Approach Life, How We Should Support Each Other," on July 2, 2011

Deeken has received many awards for his promotion of death education, including the highly prestigious Kikuchi Kan cultural award in 1991 and the Cross of the Order of Merit of the German Federal Republic in 1998.

Now, although he retired from the university in 2003, Deeken is still busy lecturing on life and death all around Japan. He did, however, find time to meet with The Japan Times at Sophia University on July 19.

Let me ask you about your background. What made you start thinking deeply about death?

I began thinking about death at an early age. When I was 8, I experienced the death of my young sister from leukemia. In grade school, I experienced many deaths during the Allied bombings in northern Germany in World War II. Some of my classmates were burned to death before my eyes in incendiary attacks. On the last day of WWII, my grandfather, who had risked his life in the anti-Nazi movement, was standing in front of our house, waving a white flag welcoming the Allied troops. He was shot in front of my eyes by the first arriving Allied soldier.

Through all those experiences, I began to think deeply about death, and make a distinction between an unavoidable death, as in the case of my younger sister, and avoidable deaths brought about by the warmongering of Germany's irresponsible Nazi government.

In retrospect, an important inspiration for choosing the philosophy of death and death education as my academic life's work came from my sister Paula, who died at home at age 4. She had been told by her doctor and by our parents that there was no cure for her leukemia and that she would have to face death soon. At that time there was no cure for leukemia. In our family there were eight brothers and sisters, so we took turns sitting at the bedside of our dying sister. She amazed all of us with the way she faced her approaching death.

As children of pious Catholic parents we had, of course, been told that for Christians death is not the end of everything but the gate to heaven. Our sister surprised us on her last day when she shook hands with everybody and simply said "I shall see you again in heaven." That enormous spiritual energy of hope was the testament of our dying sister to her parents and her seven brothers and sisters.

Read the full feature
(C) The Japan Times
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Credit: Reports and photographs are property of owners of intellectual rights.
Seniors World Chronicle, a not-for-profit, serves to chronicle and widen their reach.

July 19, 2011

THAILAND: Thai researchers conquer disabilities

BANGKOK, Thailand / The Nation / Technology / July 19, 2011

NEW TECHNOLOGIES By Jirapan Boonnoon
The Nation

Information technology is rapidly expanding its role in the lives of most people. But while most of us think of IT in terms of business and professional support, communications and entertainment, there are a growing number of disabled and elderly people for whom information technology is lifting a severely handicapped existence up to near normalcy.

Many information-technology applications, designed to improve the quality of life of disabled children and adults and elderly people, will be highlighted at the fifth International Convention on Rehabilitation Engineering & Assistive Technology (i-CREATe 2011), which opens at the Swissotel Nai Lert Park in Bangkok on Thursday.

The following are two (of the three) such applications, developed by researchers in Thailand, that will fall under the spotlight at the three-day conference.

Brain-controlled wheelchair


This project developed a hybrid EEG-EOG brain-computer interface system for practical machine control. It was undertaken by a student team from the Department of Biomedical Engineering in Mahidol University's Faculty of Engineering.

Team leader Jetsada Arnin said existing brain-computer interface systems had practical problems, including accuracy with various subjects, the number of sensors required and time for training the subject.

In the Brain-Controlled Wheelchair Project, the team proposed a hybrid framework for the brain-computer interface that would be more practical for machine control.

An electrooculogram (EOG), which measures the difference in the electrical potential between the front and back of the eye in response to dark and light, is used to control the machine in the left and right directions, while an electroencephalogram (EEG), which uses electrodes placed on the scalp to measure electrical activity in the brain, is used to control the machine's forward motion, no action, and complete stop.

The team found in the two years it took to develop the system that by using only two-channel biosignals, it could achieve average classification accuracy of more than 95 per cent.

As well, to enhance the system's efficiency, automatic controls were added. These consist of an automatic forward and prevention module. An infrared sensor is used to detect obstacles while the wheelchair is moving, and automatic forward is used to control line tracking.

The system, which works under the control of measured brain waves, aims to help people with limb paralysis to control an assistive device. It is backed up by a call centre which is able to both monitor the movements of the wheelchair and control them.

"We were inspired to develop this project because we believed that disabled people should be able to find an important place in their family and society. We wanted to improve their quality of life, so they can reach any goal, like normal people," Jatsada said.

Brain-based neurofeedback device

Mahidol University's Department of Biomedical Engineering has succeeded again with a device designed to treat children with attention deficit/hyperactivity disorder (ADHD).

The leader of the student team that developed the device, Supassorn Rodrak, said ADHD was a brain disorder suffered by 6.5 per cent of children in Thailand. The usual treatment involves drugs, and these often have side effects like vomiting, dizziness and headaches.

This hybrid EEG-HEG based neuro feedback device can help with disorders associated with hyperactivity. (Photo courtesy: Bangkok Post)

The device developed at Mahidol University uses brain signals and blood-oxygen levels in the frontal brain to deliver an alternative treatment called neurofeedback, in which the brain is taught through feedback how to improve its regulation and work more optimally.

Supassorn said the signals normally used in neurofeedback were electroencephalograms (EEG), which measured changes in the brain's electrical activity, and hemoencephalograms (HEG), a measure of brain blood flow that changes along with blood oxygenation.

The Mahidol team set out with the knowledge that both signals had advantages and drawbacks. It proposes that its hybrid EEG-HEG neurofeedback device eliminates the disadvantages of both signals and employs them both to achieve the highest accuracy.

(c) 2007 www.nationmultimedia.com
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Credit: Reports and photographs are property of owners of intellectual rights.
Seniors World Chronicle, a not-for-profit, serves to chronicle and widen their reach.

July 4, 2011

USA: Beyond the Breathalyzer - Seeking Telltale Signs of Disease

NEW YORK, NY / The New York Times / Business Day / July 3, 2011

NOVELTIES
By Anne Eisenberg

PEOPLE who are worried about bad breath often reach for a toothbrush, a Tic Tac or an Altoid. But in the future, personal breath monitoring may include far more than breath fresheners.

Scientists are building sophisticated electronic and chemical sniffers that examine the puffs of exhaled air for telltale signs of cancer, tuberculosis, asthma and other maladies, as well as for radiation exposure.
“There are clear signatures in the breath for liver disease, kidney disease, heart disease” and diseases of the lungs, said Dr. Raed Dweik, director of the pulmonary vascular program at the Cleveland Clinic, who studies breath analysis. “My sense is that breath analysis is the future of medical testing, complementing many of the blood and imaging steps we do today.”

“My sense is that breath analysis is the future of medical testing,” says Dr. Raed Dweik, holding a breath sensor he is developing. Jim Lang/Cleveland Clinic

“Breath is a rich matrix that can reflect our state of health or disease,” Dr. Dweik said. In fact, he observed, breath is so rich in chemical compounds that fully understanding it has proved challenging. Each exhalation contains gases like carbon dioxide, of course, but also the volatile remains of recent snacks, medicines and even compounds inhaled from things like carpeting, upholstery or various kinds of air pollution.


But monitors can sort out these exhaled substances with increasing sensitivity, bringing breath analysis closer to widespread use as a noninvasive tool in medical diagnosis and treatment.

Menssana Research, a biotechnology company in Fort Lee, N.J., is testing a desktop system called BreathLink for use in rapid identification of active pulmonary tuberculosis and other diseases, said Dr. Michael Phillips, the company’s chief executive and a professor of clinical medicine at New York Medical College in Valhalla, N.Y.

Anirudh Chaturvedi of Menssana Research demonstrated its BreathLink system. Menssana Research

The system is designed to work wherever there is an Internet connection.
Its analyzers can detect compounds in the breath in concentrations of parts per trillion — a billion times more sensitive than breath analyzers used by the police to detect blood-alcohol concentrations, Dr. Phillips said. To use Breathlink, a person breathes into a long tube, and a breath sample is collected and analyzed within the apparatus. The device can then detail chemical concentrations of the breath in graphics.

To read further, click here

© 2011 The New York Times Company __________________________________________________________
Credit: Reports and photographs are property of owners of intellectual rights.
Seniors World Chronicle, a not-for-profit, serves to chronicle and widen their reach.

July 1, 2011

CANADA: Five signs you need life insurance

TORONTO, Ontario / The Globe and Mail / Personal Finance / July 1, 2011

Household Finances

Five signs you need life insurance

Tim Begany
Investopedia.com


With all the hype about gold, stocks and the economy, you may have forgotten other key aspects of personal finance, like life insurance. For many, or maybe even most of us, life insurance is actually a bigger concern. If you or I died prematurely, how else could we protect our loved ones from financial hardship? Advisors will often tell you if you’re short of funds and have to choose between investing and buying life insurance, get the insurance. (Would your death leave loved ones financially stranded? Find out how to ease your mind and keep them protected. Check out Life Insurance: Putting A Price On Peace Of Mind.)


More from Investopedia

• How Much Life Insurance Do You Need?
• 5 Types Of Insurance You Can (And Should) Afford
• 5 Health Insurance Considerations
• 5 Money-Saving Insurance Tips For Couples
• 6 Bizarre Celebrity Insurance Policies

Although most people could use at least some life insurance (if only to cover their own funeral expenses), not everyone absolutely has to have it – like a retired suburban couple with $3,000,000 in savings, no children, no mortgage or other major debt, and no college expenses. If one spouse died, the other would probably be just fine financially.


So how do you know if you’re a candidate for life insurance? Here are five signs you need the coverage.

How to become a millionaire

1. You’re Married with Kids
If you’re hitched and have one or more children, life insurance is crucial. If you or your spouse died, the surviving spouse would need the money to keep up with car payments, buy food and clothes for the kids, save for college and retirement, and cover all the other everyday expenses the deceased person would no longer be around to help with. It’s not something anyone likes to think about, but it’s good to know money would be less of an issue if something happened to you or your spouse.

You might both want to buy life insurance even if you don’t have kids yet or don’t ever plan to. The sooner you get the coverage, the cheaper it’ll be. Besides, you’d probably want your spouse to be taken care of if you died prematurely, even if there weren’t any kids in the picture

2. You’re Single but Caring for an Aging Parent
Like couples with children, singles who are the main caretakers of an elderly and/or ill parent would probably feel much better knowing the parent is taken care of financially in the event of the caretaker’s premature death. That’s especially true if the parent would have no other way to pay for a professional replacement, which is extremely expensive. The services of a licensed home health aide, for example, now cost $19 an hour, on average. So the bill for even just a few daily hours of those services a day could easily surpass $20,000 in the course of a year.

3. You Have a Mortgage
You may have heard of at least one case in which somebody’s husband or wife died and they had to sell the house and move because they could no longer afford the mortgage. Life insurance can prevent that by providing cash to keep up with mortgage payments or perhaps even pay off the entire loan in one shot, if the policy is big enough. (Before tapping your home equity, find out what can go wrong. See Reverse Mortgage Pitfalls.)

4. You Own a Business and Have Partners
Business partners should always have life insurance on each other in case one of them dies, which can devastate a business because the deceased partner’s daily contribution to its success is lost. Insuring the partners’ lives can provide cash to help keep the business running in the event of someone’s death.

5. It’s Your Only Way to Give to Charity
Some people are well off enough that their death wouldn’t cause undue hardship for loved ones, but they don’t have anything extra to leave to a charity they want very much to help. They can solve this dilemma by purchasing life insurance and naming the charity as a primary beneficiary of the policy.

The Bottom Line
Don’t let the constant barrage of bad economic news and concern about your investments distract you from other important personal finance issues such as life insurance. At this point, getting adequate life insurance might actually be a higher priority for you than investing. Strongly consider purchasing coverage if there’s anybody who would suffer financially if you died. (There are many benefits to owning a life insurance policy – if you get the right one for you. See Life Insurance: How To Get the Most Out Of Your Policy.)

© Copyright 2011 The Globe and Mail Inc

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Credit: Reports and photographs are property of owners of intellectual rights.
Seniors World Chronicle, a not-for-profit, serves to chronicle and widen their reach.

June 20, 2011

USA: Elder care goes high tech

Better Aging Through Technology
By Big Think Editors
Old Time Wheelchairs















What's The Latest Development
Technology companies like General Electric and Intel are beginning to market a new industry in patient care called "aging in place". The industry relies on new monitoring technology that may effectively replace retirement homes and assisted living centers. Dorothy Rutherford, an 86 year-old retiree in Portland, Oregan, is testing some of the technology: "Motion sensors along hallways and ceilings record her gait and walking speed. A monitor on her back door observes when she leaves the house, and another one on the refrigerator keeps tabs on how often she's eating."

What's the Big Idea?
Retirement homes and assisted living centers are often difficult compromises families feel they need to make, both for the benefit of the aging parent's health and their own professional life—taking care of an aging person often requires a part-time work load outside the home. The two main appeals of new "aging in place" monitoring technology is to keep the elderly comfortable in their own home and allow their families to get back to work. Ms. Rutherford said the technology also gives her a sense of security about her health.
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Elder care goes high tech

LOS ANGELES, California / The Los Angeles Times / Business / June 17, 2011

Games, monitors and robots are among the tools being tested to help aging people live in their homes as long as possible, while lowering risks to their health and safety.

By Walter Hamilton, Los Angeles Times
 
Dorothy Rutherford is anxiously typing at her home computer, filling in answers to an online spelling game.

"I hate it when I can't get this last word," the 86-year-old retiree says as she studies the jumbled letters "nadobna." Rutherford tries "banana," then "bandana," to no avail. She smiles broadly when the computer beeps its approval of "abandon" a few moments later.

Tracy Zitzelberger at Oregon Health & Science University shows the
videoconferencing capabilities of a 4-foot robot known as Celia.
(Benjamin Reed, For The Times)

Rutherford isn't just whiling away the hours in retirement. She is on the front lines of an initiative to help elderly Americans stay in their homes as long as they can — a concept called aging in place.
Gerontologists say aging in place vastly improves the quality of life for seniors and is a lot cheaper for society than group homes and institutions.

The trick is to do so without jeopardizing the health and safety of older people, which is why Rutherford is playing the word jumble game. The results of the game, as well as typos and even the intervals between keystrokes, are monitored for abnormalities that could foreshadow physical or mental infirmity.

Tracy Zitzelberger (photo below)

She is one of 480 people taking part in several pilot programs in Portland, Ore., that outfit homes with technology so elderly people can be monitored for illness or infirmity.

The studies are being conducted by the Oregon Center for Aging & Technology at Oregon Health & Science University, with partial funding from Intel Corp. With the first wave of baby boomers turning 65 this year, corporations such as Intel see lucrative new business opportunities tending to a generation of people accustomed to doing things their own way.

"This is a race to see who's going to invent 21st century care services for boomers," said Eric Dishman (photo on right), health policy director at Intel-GE Care Innovations, a joint venture that Intel formed this year with General Electric Co. "Worldwide, there's this enormous market opportunity."

To that end, Rutherford's two-bedroom condominium has been outfitted with an array of electronic monitoring gear that might eventually find its way to retail shelves — all of it light years away from those rudimentary medical-alert necklaces advertised in an endless loop of TV commercials.

Motion sensors along hallways and ceilings record her gait and walking speed. A monitor on her back door observes when she leaves the house, and another one on the refrigerator keeps tabs on how often she's eating.

A few months ago, the former waitress even tested a robot with a Skype-like video monitor that lets faraway relatives check on loved ones.

Rutherford's granddaughter Katie Cooper piloted "Celia" from home in rural Wyoming, steering the machine — shaped like a 4-foot paper clip on wheels — around Rutherford's house as they spoke.

At first, Cooper struggled to control Celia, bumping the robot into tables and running over a shopping bag. But she got the hang of it quickly.


"My grandmother's furniture hasn't changed in 20 years. I knew the layout of the house," she said. "Anybody who's ever played a video game would have no problem using this."

The equipment in Rutherford's home is monitored by researchers at the Oregon lab, which was established in 2004 and developed most of the gear.

The lab includes a "model home" to test new gadgets. One is a special bed laced with sensors to assess breathing patterns, heart rate and general sleep quality. If someone lying on the bed holds a breath for a few seconds, the computer monitor flashes "subject has stopped breathing."

A pill box fitted with electronic switches records when medication is taken. And a Wii video game system has been rejiggered so that players stand on a platform that measures their weight and balance.

More is on the drawing board at the Oregon tech lab and elsewhere: software to help dementia patients find their way home if they get lost, devices that interpret facial expressions for signs of depression and robotic "pets" that have lifelike interactions with seniors.

For it all to catch on, however, major obstacles must be overcome. Among the biggest are persuading families to shell out several hundred dollars or more for sensors, and monthly monitoring fees that can top $100. Neither Medicaid nor most private insurance policies cover these expenses, said Dr. Jeffrey Kaye (photo on right), director of the Oregon aging and tech lab.

Another roadblock is awareness: By the time families find out about this technology, their elders may already be in need of direct supervised care, Kaye said.

And some companies market products to home-healthcare agencies that care for the homebound population, rather than directly to seniors themselves.

"Aging in place is starting to hit a tipping point, but we now need to make it mainstream enough where it's not something you find at the doctor's office or have to do lots of research on over the Web," said Joseph Coughlin, director of the MIT AgeLab.

Copyright 2011 Los Angeles Times

June 15, 2011

USA: Instead of grafting new skin to burned area, spray it on

NEW YORK, NY / The Economist / Blogs / June 15, 2011

Science and technology
BABBAGE


Skin transplants
No more hard graft?

 
REPAIRING the skin of those who have been burned is a process of autotransplantation. First, the surgeon removes the scorched tissue from the affected area. Then he takes a patch of healthy skin from elsewhere on the patient’s body, stretches it to fit the affected area and, that done, fixes it to the wound with sutures, staples or glue. In the hands of a skilled operator such grafts are nearly always successful, but the process could surely be improved on.

That, at least, is the view of Jörg Gerlach of the University of Pittsburgh. And he—and, working separately, Fiona Wood, a plastic surgeon based in Perth, Australia—have therefore come up with a neat improvement: instead of grafting new skin to the burned area, they spray the new skin on.

The source of the spray-on skin is the same as that of a traditional graft—a piece of undamaged skin tissue from the patient in question. But once this tissue has been removed, the treatment is completely different. First, the excised skin is bathed in an enzyme solution that separates its cells from one another. Then, using a syringe or a pneumatic spray, the surgeon squirts the cells on to the wound. The whole process, including the separation of the cells, can be completed in 70-90 minutes (a traditional skin graft takes between ten minutes and an hour, depending on the size of the affected area), and the burns thereafter heal at the same rate as those which have received traditional grafts, recovering fully after 12-13 days.

One advantage of the new method is the amount of coverage that can be achieved with a given amount of healthy skin. In a normal graft, the skin is stretched to three or four times its original size before being attached to the wound. That reduces the amount that needs to be taken, but stretching any further risks mesh-like scars appearing in the healed area.

The new method, however, can cover an area at least 20 times the size of the healthy skin it uses. The sprayed cells form islands across the burn and multiply rapidly to create a continuous surface. Indeed, Dr Wood says she has been able to use a piece of skin the size of a postage stamp to cover a burn across the whole of child’s chest.

There are other benefits, too. The researchers suggest spray-on skin results in less scarring than normal grafting, even when a graft has not been overstretched. And the need to remove only a small piece of skin means it is easier to match the colour of the grafted tissue to the place where it is going. In fact, Dr Wood says she sometimes sands down existing, discoloured burn scars and sprays them with skin cells to achieve a better tone.

In a study published earlier this year, Dr Gerlach describes treating eight burn patients with a skin spray. All had second-degree burns (those that destroy the epidermis, but only part of the underlying dermis) that had not been given grafts because the doctors treating them had thought the burns in question would heal in a satisfactory way without them. In these cases, though, that judgment proved incorrect and the burns had failed to heal. This kind of delayed recovery is often associated with unsightly scarring. At least two weeks after the patients were burned—on their legs, hands, faces and, in two cases, their penises—the misdiagnosed patients were given a skin spray. All recovered without complications, and the aesthetic results were judged excellent.

For the moment, the skin spray is being used mainly as a treatment for second-degree burns. For third-degree burns (those in which the dermis has been destroyed as well) spraying only works in conjunction with a graft, as spraying alone cannot, at the moment, regenerate dermal tissue. That may change, though. Dr Gerlach is investigating ways of extracting and spraying the special stem cells needed to regenerate dermal tissue, too.

Not surprisingly, one of the main interested parties in all this is the armed forces. In America, the Armed Forces Institute of Regenerative Medicine is thinking of paying for one of Dr Gerlach’s trials. The disfigurement by burning of airmen during the Battle of Britain was one of the impetuses for the early development of plastic surgery.

The work of Dr Gerlach and Dr Wood, then, continues an old tradition of trying to return wounded soldiers from the battlefield with their looks—and thus their self-esteem—intact, as well as their health.

Copyright © The Economist Newspaper Limited 2011

June 14, 2011

IRELAND: It's never too late to make new friends

DUBLIN / Irish Independent / Lifestyle / June 14, 2011

Socialising can be a problem as you get older but
Cultural Companions aims to change all that

RETIRED ship's captain Tony O'Grady loves the theatre, enjoys jazz and wouldn't be averse to a trip to the National Concert Hall or the Leopardstown races. The problem is, he's got no-one to go with.

As he avoids driving after dark and dislikes being alone in the city at night, he tends not to attend such events.

But that's all about to change, thanks to the launch of Cultural Companions, a new scheme to provide more opportunities for older people to enjoy the culture and arts scene.

The project, which piloted last month with events in Dublin and Cork, aims to develop local networks of people over the age of 55 who can meet regularly and go out together to such events, either with another person or as part of a small group.

"We'll be organising a series of events as opportunities for people to meet up and to get to know each other. These can be anything from going to films to lectures about art," says programme manager Emma Connors.

"Friendships will grow out of that and people may start organising trips for themselves. Every fortnight or so, we'll be inviting our members to an event."

As part of the programme, organisers are looking to recruit volunteers who can offer transport or companionship to people who would like to be involved in the initiative.

For pensioner Tony, who lives near Enniskerry in Co Wicklow, it's just what the doctor ordered.

"It's exactly the kind of thing I was hoping somebody would set up! I see Cultural Companions as a way to open the door for people, particularly those living alone. I see it as a network of friends with mutual interests that they can enjoy together.

"It's a way of being able to get out and go places I wouldn't be able to go to on my own -- the Japanese Gardens, Collins Barracks, the Leopardstown races or even a picnic in the Wicklow mountains.

"I do drive, but because I don't have a companion I tend not to go places. Yet I'm very interested in outings," says the 74-year-old.

"It means that I'm able to enjoy outings that I previously wouldn't have been able to engage in because of lack of a companion.

"All these things tend to be on in the evening and I don't really like driving after dark or being out late on my own, from a security point of view -- I'd feel safer if I wasn't alone."

His enthusiasm is mirrored in the avalanche of responses to advance publicity about Cultural Companions, which is an offshoot of Bealtaine, the national festival celebrating creativity in older age.

Before the Dublin launch of Cultural Companions even took place last month, 70 people had signed up, says Connors -- she's been getting an average of 10 enquiries a day about the scheme.

Interest in Cork, where the programme was launched recently, has also been very encouraging.

"People are phoning either because they don't have the same social networks that they used to have, they've relocated to a new house or have been bereaved and find they don't have an opportunity to go anywhere. Or simply that their friends are not interested in the same things they're interested in."
Funded by the Bord Gáis Foundation and developed by Age & Opportunity, a group whose aim is to increase the participation of older people in society, Cultural Companions will focus primarily on Cork and Dublin for the next few months but a national expansion is in the pipeline.

"We are already getting calls from places like Donegal, Limerick and Wexford asking about it, so from October we would look at rolling it out around the country," says Emma.

Cultural Companions is just what retired secretary Deirdre Connors, who lives alone in Kimmage, has been looking for. The sixty-something, who says her friends aren't interested in attending art or cultural events regularly -- they have other commitments -- has a wide range of interests but, like Tony, has difficulty in finding somebody to go out with.

"I like the theatre and attending concerts and I enjoy visiting art galleries -- the problem is finding someone to go with on a regular basis.

"Now I'm hoping to meet people of a like mind. Although I couldn't afford to go to the theatre every single week, there are lots of things that cost nothing -- visiting museums, art galleries. It'd be really lovely to go to with someone who enjoys it as much as I do and who has the time for it.

"I'd be interested in forming friendships with someone who goes to Cultural Companion events and who would also be interested in other outings, maybe going to other cities as well as Dublin."

Cultural Companions is free to join and, as part of setting up a recognisable brand for the organisation, members will receive a keyring and badges.

"This is not about organising trips for older people, it's about setting up a network which allows opportunities for friendships to grow naturally," emphasises Emma.

"One woman who phoned me was just getting over cancer and was living on her own and has struggled to go out."

Bealtaine coordinator Rebecca McLaughlin points to the proximity of two women who each contacted Cultural Companions to put their names on the list.

"They live less than 20 doors apart on the same street and had no idea that the other wanted to go to stuff!

"We know there are real issues and barriers preventing people from taking part in arts and cultural activities -- transport, booking tickets or lack of people to go with.

"Over 100,000 people take part in the Bealtaine festival but we know that if we can tackle those barriers, it may allow opportunities for many more older people to engage more actively in the arts."

The idea for the scheme was born when Rebecca heard about an elderly lady whose husband had recently died.

"This lady wanted to go to something but had nobody to bring her so another lady volunteered. I came back into the office after this conversation and decided there was an opening there for something which would provide opportunities for older people to get involved in cultural events and also empower older people to help other older people."

The organisers are currently encouraging venues such as art galleries, theatres and culture centres to get involved. In this context, it is worth noting that currently 11pc of the population, or 436,000 people, are over the age of 65.

It's predicted that by 2021 the figure will rise to 15.3pc. Other facts worth noting are that 89pc of older people are self-sufficient and in this country, the 65-plus age group have an income of €46.6bn.

"We would hope that such venues would see it as good business and would want to develop older audiences," says Emma.

As part of that she hopes businesses would offer special rates or discounts or organise talks with artists.

For more information contact Emma Connors on 01 8535178 or email emma.connors @ageandopportunity.ie

May 8, 2011

USA: If you’re 30 now, what can you expect at 80?

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BOSTON, Massachusetts / The Boston Globe / Seniorland / May 8, 2011

GLOBE / IDEAS/ SENIORLAND circa 2050

The future of old

If you’re 30 now, what can you expect at 80?

Getty Images
 
By Leon Neyfakh

It used to be that we knew what old age looked like. You’d work your way through adulthood, punch out as soon you turned 65, and spend the rest of your days sitting on porches, playing bridge, and golfing. And while there was a nightmare associated with old age as well — think warehouse-style nursing homes and dull, segregated retirement communities — you entered the final stage of your life expecting, probably correctly, that it would not be a long one. It’d be over before you got too sick and, perhaps more importantly, before you got too bored.

This was back when people over 65 accounted for a relatively small proportion of the US population — under 10 percent in 1960, according to the census from that year — and the average age at the time of death hovered under 70. Since then, advances in medicine and increasingly widespread health-consciousness have caused these numbers to rise precipitously. Demographers predict that by 2030, average life expectancy will have climbed past 80 and people over 65 will account for more than 20 percent of the country’s population.

Taken together, these changes amount to a dramatic transformation of American society that has only just begun — one that promises to have acute ramifications for the composition of our families, the makeup of our workforce, the functioning of our health care system, and even the layout of our cities. As America grows increasingly gray, the needs and desires of the elderly will become a more important and more visible part of the culture — and the years after age 65 will account for an increasingly large portion of our lives.

Plenty has been said about how old age is changing now. But what will it be like for those of us who won’t be hitting our 50th reunions for several more decades? Amid all the demographic projections, and all the worries about resources, we tend to assume that the actual texture of life as an old person in the future will be more or less what it is today — that even as old age lasts longer and becomes more prevalent in society, the concept itself, and the kind of life one associates with it, will remain intact. But this is a failure of imagination: In fact, old age in the future — particularly if you’re looking at 2050 and later — promises to bear little resemblance to old age as it is experienced in 2011.

Getty Images

Predicting trends in aging and preparing people for the changes ahead has become something of a cottage industry in recent years. Much of this takes the form of marketing and advice literature written by gurus promoting the so-called new old age. But there is also more serious work being done, both in academic settings like the MIT AgeLab and Stanford Center for Longevity — where researchers are studying new technologies, products, and policies geared towards making old age a less limiting and more fulfilling time in one’s life — and in private organizations experimenting with new models for how seniors with chronic illnesses might receive the care they need without being institutionalized. The American Society on Aging recently published a special issue of its journal Generations, devoted to the future of aging, and two weeks ago gathered researchers and care providers at their annual conference in San Francisco for a daylong symposium on the subject.

When these experts look ahead, they see a population of people who are less vulnerable to isolation, less likely to be bored, and more adept at using technologies to stay healthy and compensate for various ways in which life has become more difficult. They also see a population less inclined to leave the workforce — or less able to leave it — for a life of pure leisure: “Retirement” in today’s sense is likely to shrivel and be pushed later into life.

“We’re looking at people living 30 to 40 years longer than they did 100 years ago,” said Joseph Coughlin, director of the MIT AgeLab. “More of your adult life will be lived after the age of 50 than before age 50. The question is, what’re you going to do with it?”

There are still unknowns, such as how and whether America will keep funding the health care system the old now count on, or whether the prevalence of dementia will continue to grow or be vanquished by medicine. And skeptics warn against fantasies of Peter Pan-style agelessness: There is no escaping that age changes how you move and how you think. But among the most resonant — and least obvious — points that aging experts make is that old age, though a constant throughout human history, does not refer to some static set of habits, joys, and frustrations. Rather, it is an evolving condition that is continuously defined, and redefined, with every generation that experiences it.

Old age as we know it today owes much of its shape and character to a single decision the government made in 1935, when the Social Security Act set a mandatory retirement age of 65. “There was actually a theory, called ‘disengagement theory,’ that said it was mutually beneficial for older adults to remove themselves from active, productive roles in society,” said David Burdick, director of the Stockton Center on Successful Aging in New Jersey.

That idea was a product of its time. Medical breakthroughs had sent infant mortality rates down and life expectancy up, and older workers were competing with a lot more young ones for jobs. The retirement system, according to Burdick, was essentially designed to ease these obsolete old people out of the workforce to make room. And even though retirement eventually ceased to be mandatory in the United States, the Social Security Act left behind a potent legacy in marking 65 as a fault line in the public imagination between those whom our society values and those it considers no longer productive.

That fault line has started to fade in recent years, as more and more 65-year-olds elect to stay in the workforce either because they haven’t saved enough money to retire or because they just don’t feel like quitting yet. The next decade will see the line blur even further, as millions of baby boomers start reaching the line that marked the end of their parents’ careers and blowing right past it.

“You look at surveys of baby boomers, something like 80 percent of them say they want to continue working after the age of retirement,” said Richard Adler, an affiliate of the Palo Alto nonprofit The Institute for the Future, who helped organize the symposium on the future of aging at last month’s conference.

All told, by the time the boomers are done with it, old age is likely to be a very different beast than when they found it.

Some, like Marc Freedman, author of a recent book on aging called “The Big Shift,” argue that a new life stage will have emerged. Just as adolescence became a household concept in the early 20th century that was shorthand for a whole set of behaviors, desires, and difficulties, so too will this as-yet-unnamed period — starting somewhere around 55 and continuing roughly through one’s mid-80s — become synonymous with a particular mode of life, a sort of second adulthood during which a person is not only active and autonomous but motivated by new professional and personal goals. It remains to be seen whether our nation’s marketers will succeed at inventing a catchy new term to describe it.

Certain changes that age brings are unavoidable: Every generation can expect its knees to become creaky, its eyesight less keen; even very active seniors leave the house less than they once did. One reason experts foresee a more autonomous future for older people is that technology — now often seen as a cultural line that separates the oldest Americans from their younger counterparts — will increasingly integrate into people’s lives in a way that makes everyday tasks easier, not more confusing.

Some of this technology relates to health. The old need a different kind of care than younger people — steady monitoring rather than occasional trips to the doctor — and there are devices being tested in pilot programs around the country that keep a constant eye on people’s vital signs from their homes and remind them to take their medication. If you’re old, quick detection of an abnormality — a weight change from fluid buildup, a refrigerator door that can tell you haven’t been eating, even a keyboard that can tell you’ve started typing more slowly than you used to — can save a costly and dangerous trip to the hospital later.

"Many of the problems of aging are evanescent
— they come and they go"

“Many of the problems of aging are evanescent — they come and they go,”  said Tracy Zitzelberger, the administrative director of the Oregon Center for Aging and Technology at Oregon Health & Science University, which is developing a number of monitoring devices. “There are good days and bad days. When we only see our doctors on a good day because that’s when we don’t cancel our appointments, we get a very skewed assessment of our functioning. And that doesn’t get at the heart of the challenges of aging.”

The smarter our houses get, the thinking goes, the longer we’ll be able to stay in them — watched passively and remotely by nurses and family long after the point where today we’d end up in a nursing home.

Such pervasive monitoring may sound almost Big Brother-ish to someone who grew up in a world without it, but the 80-year-olds of the future won’t be those people — in fact, the hyper-networking of their homes will seem like just an extension of a life where one’s personal devices have long held and transmitted seemingly private information for the purpose of making life easier. And that’s where the cultural shift comes in: The baseline assumptions of future old people won’t be those of people who grew up in the 1940s, or even the 1960s. They’ll be shaped by people who came of age texting their friends, allowing their phones to track their whereabouts, and expecting to be generating — and receiving — information all the time.

“Younger generations are much more proficient in navigating this gray line between the physical world and the virtual world, and they’ll continue that as they age,” said George Demiris, an associate professor of biobehavioral nursing and health systems at the University of Washington.

In that sense, one of the key struggles that people face in old age — isolation and boredom — is likely to look very different in the future, if not vanish entirely for some. The people who will be facing these challenges in 40 years will be people accustomed to amusing themselves digitally, and creating a social life for themselves without another person physically present. To put it bluntly, the people who turn 70 in the year 2050 will be people who grew up playing video games. And the digital environment that now seems like a recipe for distraction — a constant feed of personal messages, links, and updates on one’s friends — starts to look a lot like a way for even a housebound person to stay engaged with the world.

This will do more than just give old people something to do — it also promises to have a significant effect on the perceived role of elderly people in society, keeping them connected to the working world for longer, and restoring some of the buying power they would have forfeited as retirees. This is part of the so-called e-Quality Theory of Aging proposed by Douglas McConatha at West Chester University in Pennsylvania. Instead of letting technology marginalize the elderly the way it did following the industrial revolution, he says, we can expect it to have a positive impact this time around, restoring elderly people’s social status by sharply reducing the number of things they can’t do and by giving them back some of their influence in the market.

There are at least two major issues looming over this happy, sunny future: the fact that 43 percent of people over 85 show symptoms of Alzheimer’s disease, and the possibility that the most promising changes up ahead will only be within reach of those who can afford them. There are those — see Susan Jacoby, author of the recent book “Never Say Die: The Myth and Marketing of The New Old Age” — who argue that any discussion about the future of old age that fails to take these issues into account is an exercise in science fiction, and even propaganda.

It is extremely difficult, if not downright impossible, to predict how these tough issues will unfold down the line. Dementia is a focus of much medical research, but so far there is little evidence that a cure is possible. And the affordability of retirement — the extent to which the 20th-century benefits contract with old people will survive — is ultimately an issue that has to be worked out politically. To the extent that it depends on postponing benefits and rationing health care for retirees, that question will be harder, not easier, to solve as the politically powerful boomer generation fills out the ranks of retirees.

Does such uncertainty mean that young people shouldn’t even try to imagine what old age will be like? Or does it mean the opposite — that we should try to nail down what we can, and brace ourselves for the rest? Because for all that stands to change politically and technologically in coming decades, one thing we can definitely count on is that the old people of the future will have been young once — and the lives they were accustomed to then will, more than anything else, determine the lives they expect to lead later. Here’s hoping the iPad 15 plays cat videos.

Leon Neyfakh is the staff writer for Ideas.
E-mail: lneyfakh@globe.com

© Copyright 2011 Globe Newspaper Company.

May 6, 2011

USA: Simply holding baby dolls makes some elders happy

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WASHINGTON, DC / US News & World Report / Family Health / Behaviour / May 6, 2011

Can 'Doll Therapy' Help Put Dementia Patients at Ease?

A Pennsylvania medical center that frequently treats older people has found that geriatric patients in need of soothing seem to benefit from a type of therapy that involves dolls.

At Geisinger Medical Center, nurses affiliated with Nurses Improving Care for Healthsystem Elders, a national geriatric program, began experimenting with what they call "baby doll therapy." The therapy includes offering dolls to elderly patients, including those with complex medical conditions who might have physical and mental limitations, and in some cases dementia or delirium -- conditions that sometimes lead to people becoming agitated during routine care.

"It is an effective therapy for improving dementia patients' quality of life," nurse Tami Underhill said in a medical center news release. "It is also one of the easier therapies, if not the easiest, to administer."

Previous research had linked the act of carrying and handling dolls to greater focus, improved attitude and enhanced communication in older people with dementia. According to the Alzheimer's Association, hospitals, nursing homes and hospice care facilities have tried baby doll therapy.

"Not only do we want our patients to be healthy, but we want them to be happy," Underhill said. "The dolls are just a simple means to that end."

Mother Holding Baby
by Keith Haring, 1958-1990

American artist, famous for his street art

More information
The U.S. National Institute of Neurological Disorders and Stroke has more about dementia.


Copyright © 2011 U.S.News & World Report LP

April 30, 2011

USA: Small changes enough to keep aging seniors in homes

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OKLAHOMA CITY, Oklahoma / NewsOK.com / April 30, 2011

By Diane Stafford

KANSAS CITY, Mo. — Replace doorknobs with levers. Widen door frames. Install a ramp over the front stoop. And maybe add a few electronic monitoring gizmos.

Those are solutions that help the elderly — especially those with physical challenges — stay in their longtime homes.

Shirley Saathoff uses a small panic-button pendant and two-way communication system for her home. McClatchy-Tribune Photo

“Aging in place” is what the lion’s share of older Americans want. But in single-family houses, that can be hard to do.

So some aging residents move into a widening array of senior housing projects.

Others are getting by with something as simple as a new toilet — just a few inches higher — and some grab bars in the bathroom. That’s what it took to make it easier and safer for one elderly man to use his bathroom again.

“Sometimes I want to cry when I see how some older people are struggling,” said Clay McQuerry, a certified aging-in-place specialist at Missouri nonprofit Rebuilding Together Clay County, who visited the man.

Whether it’s remodeling a room or signing up for a panic button to press after falling, a growing and ever-more-advanced array of “universal design” and “assistive technology” features are available for aging homeowners.

Skyrocketing demand

Demand will skyrocket as the over-65 population booms. Futurists say elderly or infirm people living in their own homes may even have monitoring equipment that, using artificial intelligence, won’t just respond to but will help predict when emergencies might occur.

“There are so many little things we can do, so many new assistive devices that are being created to help people stay in their homes,” McQuerry said. “We just have to know about them.”

For now, fancy technology takes a back seat to remodeling and some basic call devices.

Shirley Saathoff, for example, got a small panic-button pendant and two-way communication system for her tidy Lee’s Summit, Mo., home.

“It’s a godsend, Honey,” said the 72-year-old woman of the device, which provides 24-hour monitoring. “I’ve fallen five times, and there was no one around to tell I’d fallen.”

A barrier-free shower like this one can help seniors live in their homes longer. The shower features easy entry, shower seat and an adjustable shower head.
McClatchy-Tribune Photo

Frankie Cline, 87, got new front steps and a railing at her front door, replacing a single, very tall step. She used to have to hold onto a chair on the step to get up it, but twice the chair slipped, and she fell.

“I feel like I’m living again,” Cline said. “And my friends — they’re getting old, too — can visit again. Before, they couldn’t get in my house, either.”

Saathoff entered the world of assistive technology after spending hours on the floor, her body twisted awkwardly, unable to reach her telephone just a yard away.

Yet she remains adamant: “I don’t want to go to a nursing home. I love my home.”

But like most aging Americans, she can’t stay in her familiar, private surroundings without help.

Once a baker who spent hours on her feet, Saathoff now can barely get into her tiny kitchen. Her walker, which she needs to move around, doesn’t fit. So, slowly and unsteadily, she parks the walker and leans heavily on a chair, then the counter to spend a few minutes preparing a meal.

Panic button

Saathoff pays $34.95 a month to lease the panic button service, which includes a two-way communication unit smaller than a cereal box. It sits next to her phone on a small table in her living room.

Her Home for Life Solutions equipment, monitored 24/7 through a call center managed by John Knox Village, is sensitive enough to pick up her voice from anywhere in her one-bedroom apartment if it’s activated by a push of her pendant button.

“I push it, and they call me through the box,” Saathoff said. “I answer and they hear that I’m OK, or I don’t answer and they send the paramedics.”

McClatchy-Tribune Information Services

© 2010 Produced by NewsOK.com

April 16, 2011

INDIA: Offering a smart and sweet solution for diabetics

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MUMBAI / Daily News & Analysis / Money / Interview / April 16, 2011

By Lison Joseph

For over 50 million diabetic patients in India, the work of Mayur Sadawana (26), a doctoral student in biomedical engineering at the Indian Institute of Technology in Mumbai, would mean less needle pricks.

A patient suffering from diabetes is unable to process sugar for meeting the energy requirements of the body. In response to this, human body breaks down stored fat in the body to fuel the energy needs. But this process results in an acidic by-product called ketones. Excess of ketones in blood is poisonous and the condition is called diabetic ketoacidosis. Every diabetic patient is prone to this condition.

Present DKA diagnosis methods use glucose estimation and monitoring techniques. For follow-up treatment, electrolytes, blood acid balance and oxygen concentration in blood are constantly monitored which requires multiple needle-pricks for collecting blood sample.

Sadawana has developed a small diagnostic device that looks like a pen and can diagnose diabetic ketoacidosis with fair amount of accuracy with one drop of blood sample. The device, once commercially available, promises to bring down the cost of diagnosis and increase the accuracy of test compared to existing medical devices.

Sadawana tells DNA his technique combines nano technology, photo-luminescence and a micro-chip to accurately diagnose diabetic ketoacidosis.

Error factor in his technique range from 4-9% compared to 20% in existing tests. Best of all, it brings down the cost of a test to Rs100.

Is this your first idea that clicked?
Yes. This is the first among the few ideas that I planned in the medical field. However, this was not the priority, as I thought it was not possible for me to build such a device, until I started my masters in biomedical engineering.

What are you currently working on?
I am developing a point-of-care multi-analyte sensor for diabetic ketoacidosis patients.

Would you work independently with funding or as part of a research institution?
Working independently with funding gives an opportunity to form a great team. However, I love working with my guide Rohit Srivastava as he gives us the freedom to work and motivates us for out-of-box thinking. After my PhD, I would like to work as an individual. I have made plans for the future, but require funding for it.

Is innovation an end in itself or a means to become an entrepreneur?
Innovation is one of the means to become an entrepreneur. Diagnostics is what I like and what I’m going to do for a living, either by practicing medicine or by innovating diagnostic devices.

Does India value and reward its innovators?
I can’t say about other innovators but at least for me, it’s so far, so good. India is a land of opportunities. Recently, I attended a workshop on entrepreneurship, which stated ‘changes bring opportunity’. India is a land where changes happen too often.

Has your innovation made material difference to your standard of living?
My innovation has not made any difference to my standard of living. But it has definitely made a difference in the way others perceive me. After graduating as MBBS, diversifying into engineering and research was not easy and the TR35 India award validates my capability.

Who are your biggest influences?
My father. His general practice and diagnostic skills were the only reason for me to stick to medicine. My mom and my fiancee are very supportive. My brother is my strength and support.

What has been your biggest mistake?
None.

If you could go back and change one thing about your life as an innovator, what would it be?
I would have liked to have done engineering first and then medicine. Now I need a little more time to understand the engineering concepts, as I don’t come from an engineering background. But my passion drives me to the shore eventually.

Did you have a childhood dream?
Yes. To be an automobile engineering and make cars that run on sea.

©2011 Diligent Media Corporation Ltd

October 13, 2010

USA: Lies, Damned Lies, and Medical Science

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WASHINGTON DC / The Atlantic Magazine / November Edition / October 13, 2010

Brave Thinkers

Much of what medical researchers conclude in their studies is misleading, exaggerated, or flat-out wrong.

So why are doctors—to a striking extent—still drawing upon misinformation in their everyday practice?

Dr. John Ioannidis has spent his career challenging his peers by exposing their bad science.

By David H. Freedman



















Dr. John Ioannidis. Image credit: Robyn Twomey/Redux


In 2001, rumors were circulating in Greek hospitals that surgery residents, eager to rack up scalpel time, were falsely diagnosing hapless Albanian immigrants with appendicitis. At the University of Ioannina medical school’s teaching hospital, a newly minted doctor named Athina Tatsioni was discussing the rumors with colleagues when a professor who had overheard asked her if she’d like to try to prove whether they were true—he seemed to be almost daring her. She accepted the challenge and, with the professor’s and other colleagues’ help, eventually produced a formal study showing that, for whatever reason, the appendices removed from patients with Albanian names in six Greek hospitals were more than three times as likely to be perfectly healthy as those removed from patients with Greek names. “It was hard to find a journal willing to publish it, but we did,” recalls Tatsioni. “I also discovered that I really liked research.” Good thing, because the study had actually been a sort of audition. The professor, it turned out, had been putting together a team of exceptionally brash and curious young clinicians and Ph.D.s to join him in tackling an unusual and controversial agenda.

Last spring, I sat in on one of the team’s weekly meetings on the medical school’s campus, which is plunked crazily across a series of sharp hills. The building in which we met, like most at the school, had the look of a barracks and was festooned with political graffiti. But the group convened in a spacious conference room that would have been at home at a Silicon Valley start-up. Sprawled around a large table were Tatsioni and eight other youngish Greek researchers and physicians who, in contrast to the pasty younger staff frequently seen in U.S. hospitals, looked like the casually glamorous cast of a television medical drama. The professor, a dapper and soft-spoken man named John Ioannidis, loosely presided.

One of the researchers, a biostatistician named Georgia Salanti, fired up a laptop and projector and started to take the group through a study she and a few colleagues were completing that asked this question: were drug companies manipulating published research to make their drugs look good?

Salanti ticked off data that seemed to indicate they were, but the other team members almost immediately started interrupting. One noted that Salanti’s study didn’t address the fact that drug-company research wasn’t measuring critically important “hard” outcomes for patients, such as survival versus death, and instead tended to measure “softer” outcomes, such as self-reported symptoms (“my chest doesn’t hurt as much today”). Another pointed out that Salanti’s study ignored the fact that when drug-company data seemed to show patients’ health improving, the data often failed to show that the drug was responsible, or that the improvement was more than marginal.


Salanti remained poised, as if the grilling were par for the course, and gamely acknowledged that the suggestions were all good—but a single study can’t prove everything, she said. Just as I was getting the sense that the data in drug studies were endlessly malleable, Ioannidis, who had mostly been listening, delivered what felt like a coup de grâce: wasn’t it possible, he asked, that drug companies were carefully selecting the topics of their studies—for example, comparing their new drugs against those already known to be inferior to others on the market—so that they were ahead of the game even before the data juggling began? “Maybe sometimes it’s the questions that are biased, not the answers,” he said, flashing a friendly smile. Everyone nodded. Though the results of drug studies often make newspaper headlines, you have to wonder whether they prove anything at all. Indeed, given the breadth of the potential problems raised at the meeting, can any medical-research studies be trusted?

That question has been central to Ioannidis’s career. He’s what’s known as a meta-researcher, and he’s become one of the world’s foremost experts on the credibility of medical research. He and his team have shown, again and again, and in many different ways, that much of what biomedical researchers conclude in published studies—conclusions that doctors keep in mind when they prescribe antibiotics or blood-pressure medication, or when they advise us to consume more fiber or less meat, or when they recommend surgery for heart disease or back pain—is misleading, exaggerated, and often flat-out wrong. He charges that as much as 90 percent of the published medical information that doctors rely on is flawed. His work has been widely accepted by the medical community; it has been published in the field’s top journals, where it is heavily cited; and he is a big draw at conferences. Given this exposure, and the fact that his work broadly targets everyone else’s work in medicine, as well as everything that physicians do and all the health advice we get, Ioannidis may be one of the most influential scientists alive. Yet for all his influence, he worries that the field of medical research is so pervasively flawed, and so riddled with conflicts of interest, that it might be chronically resistant to change—or even to publicly admitting that there’s a problem.

The city of Ioannina is a big college town a short drive from the ruins of a 20,000-seat amphitheater and a Zeusian sanctuary built at the site of the Dodona oracle. The oracle was said to have issued pronouncements to priests through the rustling of a sacred oak tree. Today, a different oak tree at the site provides visitors with a chance to try their own hands at extracting a prophecy. “I take all the researchers who visit me here, and almost every single one of them asks the tree the same question,” Ioannidis tells me, as we contemplate the tree the day after the team’s meeting. “‘Will my research grant be approved?’” He chuckles, but Ioannidis (pronounced yo-NEE-dees) tends to laugh not so much in mirth as to soften the sting of his attack. And sure enough, he goes on to suggest that an obsession with winning funding has gone a long way toward weakening the reliability of medical research.

He first stumbled on the sorts of problems plaguing the field, he explains, as a young physician-researcher in the early 1990s at Harvard.  Continue reading....


Copyright © 2010 by The Atlantic Monthly Group.